CLONALITY ANALYSIS AND IDH1 AND IDH2 MUTATION DETECTION IN BOTH COMPONENTS OF DEDIFFERENTIATED CHONDROSARCOMA, IMPLICATED ITS MONOCLONAL ORIGIN

Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin

Dedifferentiated chondrosarcoma (DDCS) is a highly malignant tumor that belongs Ice Cream Molds to an uncommon subtype of chondrosarcoma with a poor prognosis.Microscopically, it is composed of highly differentiated chondrosarcoma and highly malignant noncartilaginous sarcomas with an abrupt interface.The question of whether the two components orig

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Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells.

New therapies are needed for metastatic breast cancer patients.Oncolytic herpes simplex virus (oHSV) is an exciting therapy being developed for use against aggressive tumors and established metastases.Although oHSV have been demonstrated safe in clinical trials, a lack of sufficient potency has slowed the clinical application of this approach.We ut

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First episode psychosis Post-COVID 19 infection : case report

Introduction During the course of COVID-19 pandemic, the respiratory system is the most commonly affected while many neuropsychiatric manifestations of the disease have been observed.Objectives Emphasize the importance of detecting psychiatric symptoms in patients infected with Covid 19.Methods Presentation of case report Results A 44-year-old woma

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A toolbox to demystify probabilistic and statistical paradoxes

There is a variety of empirical evidence that the coverage of paradoxes in mathematics education helps to support thorough understanding of probabilistic and statistical concepts.However, existing literature often focuses on extensive analysis of a specific paradox, provides new perspectives or an analysis from a different angle.Often neglected asp

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